Ipamorelin is a pentapeptide. Five amino acids. That's it. But three of those five don't exist in nature. The sequence: Aib His D 2 Nal D Phe Lys, with a C terminal amide. Position 1 is aminoisobutyric acid the Understanding low cortisol ACTH, secondary adrenal insufficiency, hypocorticolism Maternal Pituitary Support Sheehan's Syndrome, Lymphocytic Hypophysitis Prolactin as an adrenocorticotropic hormone: Prolactin signalling is a conserved key regulator of sexually dimorphic adrenal gland function in health and disease Lalli 2022 BioEssays Wiley Online Library Cortisol Disorders