Targeting Skeletal Muscle Dysfunction With L Carnitine for the Treatment of Patients With Chronic Obstructive Pulmonary Disease In Vivo Neuroprotective effects of L carnitine towards oxidative stress and inflammatory processes: a review of its importance as a therapeutic drug in some disorders Metabolic Brain Disease Springer Nature Link Combined metabolic activators to treat mitochondrial dysfunction Mitochondrial dysfunction is a common feature of many human diseases and is emerging as a therapeutic target. Systems biology and multiomics approaches have revealed that Carnitine is an essential cofactor for transport of long chain fatty acids into mitochondria, where oxidation takes place. Carnitine deficiency leads to depressed mitochondrial oxidation of fatty acids, resulting in storage of fat