The metabolic pathways of acetaminophen (APAP) in the human body. The Download Scientific Diagram GSH reduces NAPQI, the metabolite responsible for hepatotoxicity in acetaminophen toxicity. Toxic doses increase oxidation into NAPQI, overwhelming glutathione. How does ethanol interfere with acetaminophen metabolism? Image: https: t.co 6EY9dIwLXY What Are the Potential Sites of Protein Arylation by N Acetyl p benzoquinone Imine (NAPQI)? Chemical Research in Toxicology Paracetamol toxicity Deranged Physiology
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glutathione napqi Metabolic pathway for NAPQI formation and detoxification by conjugation...