Glutathione reductase deficiency causes symptoms and treatment options Infinite Labs Elevated glutathione levels may reflect an accumulation resulting from impaired recycling, often due to deficiencies in NADPH, selenium, or riboflavin (vitamin B2). This indicates a disruption in the redox balance rather than Glutathione synthetase deficiency MedLink Neurology Correcting glucose 6 phosphate dehydrogenase deficiency with a small molecule activator Nature Communications