Frontiers Broadening horizons: research on ferroptosis in lung cancer and its potential therapeutic targets Ferroptosis: when metabolism meets cell death Physiological Reviews American Physiological Society Glutathione is a critical soldier in our line of defense. We even have mechanisms that recycle and reuse it. But what happens when our toxic burden becomes too high? Our genetic detoxification CHAC1 degradation of glutathione enhances cystinestarvationinduced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2eIF2ATF4 pathway Oncotarget
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