One carbon metabolism and schizophrenia: current challenges and future directions: Trends in Molecular Medicine Research on Antioxidant Role in Schizophrenia and Psychosis Points to Possible Therapeutic Value of Compound Found in Broccoli Brain & Behavior Research Foundation Frontiers Associations between purine metabolites and monoamine neurotransmitters in first episode psychosis The distance between a compound demonstrating efficacy in preclinical research and that compound appearing in a physician's standard toolkit can span a generation. The mechanisms by which NAC addresses oxidative stress, glutamate