FDA mulls compounding for peptides previously flagged over safety risks BioSpace Which non FDA (United States Food and Drug Administration) approved peptides, such as BPC 157 (Body Protection Compound 157) and TB 500 (Thymosin Beta 500), are likely legitimate for medical use under strict supervision? What Peptides Are Legal in the U.S.? Understanding FDA Approval, Compounding, and the Legal Gray Areas Holt Law The FDA has issued clear signals on BPC 157: it is not approved for human use in any form due to potential significant safety risks. This critical classification profoundly impacts research and commercialization