Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Consultant360 The Pigmented Hard Palate: A Long Term Outcome of Imatinib Actas Dermo Sifiliogrficas Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Solitary pigmentation of the tongue: lentigo simplex or pigmented fungiform papilla?