Unbalanced Activation of Glutathione Metabolic Pathways Suggests Potential Involvement in Plant Defense against the Gall Midge Mayetiola destructor in Wheat Scientific Reports Glutathione: Master Antioxidant, Reducing Oxidative Stress, and Detoxification Calming the Chaos: How Ozone and Light Therapy Help with Mast Cell Activation Syndrome (MCAS) in Oklahoma City Venturis Clinic Mast cells are hypersensitive immune cells that release histamine and other inflammatory mediatorsoften in response to oxidative stress, environmental toxins, and immune imbalance. Many patients with MCAS have low levels of glutathione.