Does size matter? Historically, a bigger needle gauge was considered better to prevent damage to red blood cells. However, our recent guidelines recommend using smaller gauge needles (2325 G) for all like, swipe, and save for when it's your turn to do an injection on a patient Intramuscular (IM) Angle: 90 Needle Size: 2225G, 11.5 inch Med Examples: Vaccines (e.g. Tdap, Needle and Syringe Combos What needle size is best for injec Pernicious Anaemi