Internet famous peptides like BPC 157 and TB 500 might be the future, but right now they're a shot in the dark. Many treatment guidelines for psoriasis rely heavily on body surface area (BSA) involvement to determine disease severity and eligibility for systemic therapies like biologics. Traditionally, patients with less than 10% BSA involvementespecially Frontiers Skin immune microenvironment in psoriasis: from bench to bedside Human umbilical cord mesenchymal stem cells for psoriasis: a phase 1 2a, single arm study Signal Transduction and Targeted Therapy