Changes in levels of the antioxidant glutathione in brain and blood across the age span of healthy adults: A systematic review ScienceDirect Glutathione is the body's master antioxidant. It is important for handling oxidative stress, detoxification, and immune health. Low glutathione is linked to many chronic illnesses. Knowing what your body needs to make Glutathione, often dubbed the master antioxidant plays a crucial role in detoxification, immune function, and protecting our cells from oxidative stress. Here are some signs that your levels might be low: Persistent OXIDATIVE STRESScan contribute to hypothyroid symptoms When the body has to deal with too much Oxidative Stress from inflammation, then the enzyme Glutathione Peroxidase [GPx] has to work overtime to inactivate damaging "