Figure 2 from Impact of glucose 6 phosphate dehydrogenase deficiency on the pathophysiology of cardiovascular disease. Semantic Scholar Role of Glucose 6 Phosphate Dehydrogenase (G6PD) in the Pathophysiol ogy of Cataract. Glucose 6 Phosphate Dehydrogenase (G6PD) Deficiency The Medical Biochemistry Page G6PD Deficiency Glucose 6 phosphate dehydrogenase deficiency X linked recessive disorder Leads to low NADPH, impairing glutathione regeneration RBCs are vulnerable to oxidative damage Pathophysiology: In G6PD deficiency: No