What Peptides Are Legal in the U.S.? Understanding FDA Approval, Compounding, and the Legal Gray Areas Holt Law BPC 157 aka Wolverine. This peptide is not FDA approved, but it is very popular among the biohacking population. Ashley explains the science behind it, but remember, it doesnt have human data yet, so BPC 157 Dosing (Common Protocols), Oral Subcutaneous, 500 mcg daily, Duration: 6 weeks, Intramuscular Peritendinous, 1 mg daily, Duration: 6 weeks, Note:, Not approved by FDA or Peptides Lack Reliable Safety Information, Watchdog Warns