There's a reason L carnitine keeps showing up in PCOS research Because PCOS is closely tied to insulin resistance, inflammation, and metabolic dysfunctionand L carnitine plays a role in energy metabolism and fat utilization. Acetylcarnitine Wikipedia Acetyl L Carnitine, 500 mg, 200 Quick Release Capsules Carnitine supplementation improves metabolic flexibility and skeletal muscle acetylcarnitine formation in volunteers with impaired glucose tolerance: A randomised controlled trial eBioMedicine