FOXO4 DRI Peptide for Cellular Senescence and Anti Aging Research FOXO4 DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53 serine 15 phosphorylation Communications Biology Molecular modelling of the FOXO4 TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells eBioMedicine Peptide inhibitors targeting FOXO4 p53 interactions and inducing senescent cancer cell specific apoptosis bioRxiv
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foxo4-dri senolytic study The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI