Targeting Skeletal Muscle Dysfunction With L Carnitine for the Treatment of Patients With Chronic Obstructive Pulmonary Disease In Vivo Androgen receptor density plays a meaningful role in muscle anabolism because it determines how strongly a muscle fiber responds to androgen signaling. Gabriel Alizaidy, MD, MS Increasing Androgen Sensitivity SecondLife Inhibition of androgen receptor can decrease fat metabolism by decreasing carnitine palmitoyltransferase I levels in skeletal muscles of trained mice Nutrition & Metabolism Springer Nature Link