Mast Cell Activation Syndrome and the Triad of MCAS, POTS, and Hypermobile EDS : r IBSResearch Read this paper describing a large case series of patients with mast cell activation syndrome (MCAS) and comorbidities, whose MCAS associated symptoms improved significantly on GLP1 agonists. To summarize: 47 Siglecs as potential targets of therapy in human mast cell and or eosinophil associated diseases ScienceDirect An essential role for mast cells as modulators of neutrophils influx in collagen induced arthritis in the mouse Laboratory Investigation