The FDA is signaling that perhaps immediate treatment with acetaminophen is less clearly needed for a low grade fever, especially in pregnancy, unless theres a stronger indication for it., Safer Tylenol (acetaminophen) is one of the most commonly used painkillers. It is safe for kids, during pregnancy, and while breastfeeding. However, just because it is safe, doesn't mean that it Interaction with Ethanol Alcohol Metabolism How can I minimize liver damage while taking Tylenol (acetaminophen) in relation to glutathione levels?