Not feeling well? *Don't* reach for Tylenol! Here are 8 reasons why. Some experts maintain that if acetaminophen were a brand new drug up for approval today, it would *not* get approved at Glutathione, Tylenol, and Vaccines: What Parents Need to Know Lotus Homeopathy, Inc. Yes there is good evidence that acetaminophen (the active ingredient in Tylenol) can deplete glutathione under certain conditions. But whether that matters depends on dose, duration, and individual factors. TYLENOL [Acetaminophen APAP]why it may cause harm Tylenol should likely be avoided in excess by genetically vulnerable children. GENETICALLY VULNERABLE likely meanschildren with limited supplies of GLUTATHIONE. The problem with TYLENOL