Exploring N Acetylcysteine in Psychiatry Psychiatric Times Lower Posterior Cingulate Cortex Glutathione Levels in Obsessive Compulsive Disorder ScienceDirect Glutathione and Autoimmune Disease Master Antioxidant NAC is one of those compounds that exposes how little we're taught to think in systems. Yes, it supports glutathione synthesis but clinically, its impact on ammonia clearance and glutamate regulation