Lentigo maligna and lentigo maligna melanoma Feline Iris Hyperpigmentation MSPCA Angell Amelanotic Melanoma Pictures Despite the name "melanosis," the pigment isn't melanin. The Pigment: It is actually lipofuscin, a "wear and tear" pigment. The Process: Anthraquinone laxatives cause apoptosis (cell death) of the colonic epithelial cells.
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