IGF 1 LR3 does not promote growth in late gestation growth restricted fetal sheep American Journal of Physiology Endocrinology and Metabolism American Physiological Society Localized Igf 1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle Nature Genetics Overexpression of Igf2 derived Mir483 inhibits Igf1 expression and leads to developmental growth restriction and metabolic dysfunction in mice ScienceDirect IGF 1 LR3 Injection Benefits And How It Works The HCG Institute