Peptides are often well tolerated, but they can still cause temporary reactions while the body adapts. Some commonly reported effects include: BPC 157 headaches, nausea, increased appetite TB 500 Sermorelin vs. CJC 1295 vs. Ipamorelin Livv Natural Ipamorelin Peptide Therapy Women's Health & Cosmetic Services of Maryland If youre looking at peptides to boost growth hormone, heres the key difference: Growth hormonereleasing peptides (GHRPs), like Ipamorelin, work by hitting the ghrelin receptor, your bodys hunger