Stable Gastric Pentadecapeptide BPC 157 as a Therapy and Safety Key: A Special Beneficial Pleiotropic Effect Controlling and Modulating Angiogenesis and the NO System People talk about BPC 157 like it's one thing. It isn't. Oral BPC 157 stays local. It survives digestion long enough to act on the GI mucosa, then clears before it reaches systemic circulation. Peptide Therapy for Pain Management and Healing Core Medical & Wellness Theres a lot of debate about whether BPC 157 needs to be injected or if the oral version works. The truth is, oral BPC 157 can be just as effective as injectablebut with one key adjustment. A small