The science behind hangovers The site of detoxification in your body is located in your liver. Everything that you ingest is broken down in your digestive system to become small enough Alcoholic Liver Disease: Alcohol Metabolism, Cascade of Molecular Mechanisms, Cellular Targets, and Clinical Aspects Novel physiological roles for glutathione in sequestering acetaldehyde to confer acetaldehyde tolerance in Saccharomyces cerevisiae Applied Microbiology and Biotechnology Springer Nature Link Computationally Assessing the Bioactivation of Drugs by N Dealkylation S. Joshua Swamidass, MD PhD