Glutathione deficiency can lead to a variety of signs and symptoms that affect your overall health. Here are some common signs to look out for: 1. **Increased Dark Spots** Glutathione Glutathione is such a critical soldier in our line of defense that our bodies make it themselves. We even have mechanisms that recycle and reuse it. But what happens when our toxic Glutathione deficiency and heart failure: a systematic review of human and animal evidence ScienceDirect Glutathione: What It Is, Why You Need It, How You Can Increase It The Amino Company