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Oral pigmentation in children: a diagnostic challenge Archives of Disease in Childhood Black Spots on Teeth & Gums Stains or Something Serious? Treatment of labial melanotic macules on the lip. These are benign spots that appear on the lips for no apparent reason. The causes are mostly genetic, but similar spots can appear in Frontiers A novel effect of bevacizumab in reducing characteristic pigmentation in PeutzJeghers syndrome: a case report and literature review
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