L Carnitine May Help a Fatty Liver LiverSupport.com Effect of l carnitine supplementation on lead acetate induced liver cell apoptosis and inflammation: role of caspase 3 and glycogen synthase kinase 3 enzymes ScienceDirect L carnitine is primarily synthesized in the liver from the amino acids lysine and methionine through a series of four enzymatic reactions, with the liver and kidneys converting the precursor butyrobetaine into active L carnitine Could Be Beneficial in Nonalcoholic Fatty Liver Disease Patients by Improving Choline Metabolism and Reducing Liver Biomarkers European Medical Journal