Glutathione responsive and mitochondria targeting enhanced photodynamic therapy and cascade triggered carbon monoxide release for all in one tumor therapy ScienceDirect Mast cells are hypersensitive immune cells that release histamine and other inflammatory mediatorsoften in response to oxidative stress, environmental toxins, and immune imbalance. Many patients with MCAS have low levels of glutathione. Calming the Chaos: How Ozone and Light Therapy Help with Mast Cell Activation Syndrome (MCAS) in Oklahoma City Venturis Clinic How Mycotoxins Trigger Mast Cell Activation and Brain Inflammation