Depressed teenagers twice as likely to vape, study finds Our Futures Institute Teens who vape or smoke more likely to experience depression and anxiety, study of over 60,000 u.s. students finds. Youth using both e cigarettes and traditional tobacco report the highest levels of mental Vaping is often advertised as harmless, but it has serious health effects, including worsening mental health. As expert Laura Crotty Alexander, MD, UC San Diego, explains to host Erika Moseson, MD, MA, DEPRESSION STICK Truth Initiative Mojo Supermarket